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Arista AH is an
Absorbable Hemostat that is used to assist in the
control of profuse bleeding in general surgery when
conventional procedures are ineffective or impractical.
MPH Technology
MPH (Microporous Polysaccharide Hemospheres)
represents a new process for effecting almost
instantaneous hemostasis at wound sites, even in the
presence of profuse bleeding. The technology consists of
an engineered biopolymer, microporous particle, with a
controlled pore size, which is designed to act as a
sieve to dehydrate the blood and thus serve to
accelerate the natural clotting process.
Using this technology, clotting
has been demonstrated to initiate within as little as 30
seconds to one minute, compared to as much as 30 minutes
required by traditional hemostats. Applied topically,
MPH gels rapidly with no tissue irritation, creating a
protected environment for hemostasis and healing.
The particles, or “beads,” are derived from plant-based
biomaterials with an extensive history of use in humans.
The final packaged material is stable, bio-inert and
sterile. Following is a summary of the benefits of the
technology.
MPH: Features and Benefits:
- Bio-inert – no inherent risk of disease
transmission
- Contains no human or animal proteins –
hypoallergenic
- Effective even in areas of profuse bleeding
- Stable base materials with extended shelf life
- User-friendly, one-step application with no
mixing.
- Rapid time to wound hemostasis as shown in
initial animal
studies.
Multiple cost reduction benefits for patient and
provider
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MPH: How It Works
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The microporous particles (beads), in powder form, are
applied to the wound site, even in the presence of
profuse bleeding.
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Application can be in the form of a
spray, or the powder can be contained and applied with a
variety of tools including syringes, endo-surgical
applicators, nasal surgical applicators and resorbable
dressings.
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The molecular exclusion properties of the bead create a
high concentration of platelets and other constituents
on the exterior surface as the blood is dehydrated.
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Acting as a molecular sieve, the bead absorbs fluids in
the blood, as proteins and cellular constituents adhere
to its surface.
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This gelled, compacted cells accelerate the normal
clotting cascade. The expanded beads and their load of
platelets and solids become part of a clot that initial
tests have shown to be more resilient even than a purely
natural clot.
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As the clot breaks down, the beads
dissolve enzymatically, leaving no trace of material at
the wound site within a very short period of time.
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